Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA): a Multicenter Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• At least 18 years old

• Indication for (extended or partial) lateral pancreaticojejunostomy as agreed during multidisciplinary team meeting based on symptomatic chronic pancreatitis (i.e. morphine dependent pain or recurrent acute flares of pancreatitis, at least 3 episodes per year) and a dilated pancreatic duct of ≥ 5 mm, with a non-enlarged pancreatic head \< 40 mm

• Confirmed CP, according to the M-ANNHEIM diagnostic Criteria24

• Eligible for both an robot-assisted and open approach

• Obtained written informed consent

Locations
Other Locations
Netherlands
Amsterdam UMC
RECRUITING
Amsterdam
Contact Information
Primary
E. Kilinc
e.kilinc@amsterdamumc.nl
+31652741059
Time Frame
Start Date: 2025-04-16
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 28
Treatments
Experimental: Robot-assisted lateral pancreaticojejunostomy
Active_comparator: Open lateral pancreaticojejunostomy
Sponsors
Collaborators: University Medical Center Groningen, Universitätsklinikum Hamburg-Eppendorf, Medisch Spectrum Twente, Catharina Ziekenhuis Eindhoven, St. Antonius Hospital, Radboud University Medical Center, Maastricht University Medical Center, Onze Lieve Vrouwe Gasthuis, Erasmus Medical Center, Leiden University Medical Center
Leads: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

This content was sourced from clinicaltrials.gov